Suppressive effect of secretin upon pancreatic alpha cell function

Suppressive effect of secretin upon pancreatic alpha cell function.

Highly purified secretin, infused endoportally in five conscious mongrel dogs at a rate of 10 clinical units per min for 20 min, caused a prompt and statistically significant reduction in the pancreaticoduodenal vein level of pancreatic glucagon from a control average of 1130 pg/ml (SEM+/-312) to a nadir of 492 pg/ml (SEM+/-194) 15 min later (P < 0.01). During modest hyperglycemia of about 130 ...

Inhibitory effect of pancreatic secretin on gastric secretion.

GREENLEE, HERBERT B., ENRIQUE H. LONGHI, JOSE DELGADILLO GUERRERO, THOMAS S. NELSEN, ABDUL LATIF EL-BEDRI AND LESTER R. DRAGSTEDT. hhibitwy effect of pmwreatic secretiN on gust& secretion. Am. J. Physiol. 190(3) : 396-402. 1957.---In dogs prepared with both a vagus denervated Heidenhain pouch and a total pancreatic fistula, the intravenous injection of pancreatic secretin (Lilly) produced a pro...

An exocrine pancreatic function test using secretin-chole-

cystokinin or caerulein is considered the best test possible because of its high sensitivity and specificity. However, this test is complex, time consuming, unpleasant for the patient and not feasible in some cases. Therefore, many alternative methods have been developed, such as the p-aminobenzoic acid and fluorescein dilaurate tests, serum trypsin and faecal chymotrypsin concentrations, and e...

Inhibitory Effect of Pancreatic Secretin on Gastric Secretion1

GREENLEE, HERBERT B., ENRIQUE H. LONGHI, JOSE DELGADILLO GUERRERO, THOMAS S. NELSEN, ABDUL LATIF EL-BEDRI AND LESTER R. DRAGSTEDT. hhibitwy effect of pmwreatic secretiN on gust& secretion. Am. J. Physiol. 190(3) : 396-402. 1957.---In dogs prepared with both a vagus denervated Heidenhain pouch and a total pancreatic fistula, the intravenous injection of pancreatic secretin (Lilly) produced a pro...

Secretin and pancreatic enzyme secretion.